Should we all become stoics? A new book about an elderly American man offers clues about how to embrace change in difficult times and live a satisfying and joyful life.
How to be happy by Charlie (aged 109)
Sensational centenarian: Born in Missouri, Charlie White became a medical student in 1925. Glossary
Penicillin - In 1928, Scottish scientist Alexander Fleming discovered the first antibiotic in a mold growing in his laboratory. It was used to treat an eye infection in 1930 and revolutionised modern medicine.
Antibiotic - Medicines that fight bacterial infections.
Anaesthetist - A doctor who gives patients medicines that make them unable to feel pain before surgery.