3D printing to make spare parts for bodies

Wake-up call: Will bioprinting create perfect bodies?

The medical technology of bioprinting, artificially creating human organs and body parts, is racing ahead. How long could it be before we can replace any part of our bodies?

Totally life-changing, is how Stephen Power described his operation. Two years ago a bad motorcycle accident left him with severe damage to his face. ‘I broke both cheekbones, top jaw, my nose and fractured my skull.’

For the first time in the UK, surgeons in Swansea operated on his face using 3D printing to create precisely designed artificial bones. The result has been an outstanding success. His chief surgeon said the 3D printing took away the guesswork that can be so difficult in reconstructive work: ‘I think it’s incomparable – the results are in a different league from anything we’ve done before.’

This is just the latest in a series of impressive and rapid advances for the technology. Computer-operated 3D printers which create objects layer by layer in plastic have been around since the 1980s. Now affordable versions for use at home are coming onto the market.

Recently there has been considerable research into bioprinting – in which organs and body parts are created in a similar way in living tissue. In this process, layers of living cells are deposited onto a gel medium and slowly built up to form three-dimensional structures. Last year a human ear was successfully created to correct a congenital birth defect. Transplants have also been made of bio-printed windpipes and bladders. The race is now on between biotechnology companies to see who can produce a workable, full-size bio-printed liver first.

Some suggest that in the future, damaged or worn-out organs or limbs might be as easily changed as going to the garage and putting a new set of tyres on the family car. And if that could be done endlessly, it holds out the possibility that humans could live with good health and fitness for many times our current lifespans – even, in theory, forever.

A matter of life and death

Many are predicting that at some point in the future it will be possible to replace almost any part of our body. At present there are far too few human organs available for transplant and many people die before finding a suitable match for their liver, kidney or heart. Being able to bioprint organs on demand would save thousands of lives every year.

But bioprinting also raises profound and troubling moral questions. While fewer people would die young and many would live happier, healthier and longer lives, who would control this technology? It would be an alarming prospect indeed if a company could develop organs and charge whatever it liked for their use, giving it the power of life and death over those in desperate need. And it could create a disturbing schism between those wealthy enough to be able to afford this superhuman surgery, and those growing old in their imperfect bodies.

You Decide

  1. Are there any possible dangers in bioprinting technology?
  2. If you needed a transplant would you prefer an organ from another person or one which was created by bioprinting? Why?

Activities

  1. Imagine you were able to live for 300 years. What would be the advantages and disadvantages?
  2. Discuss who should have access to healthcare and why. Should non-smokers be given lung transplants before smokers, for example? Should the ability to pay ever play a part?

Some People Say...

“Do not try to live forever, you will not succeed.’George Bernard Shaw”

What do you think?

Q & A

Living for centuries sounds great. Who wouldn’t want that?
Living longer in good health is very desirable; unhappiness in old age is often caused by ill health. But if you lived for centuries, even without disease, you might well get lonely having outlived your family and your friends. As we get older our brain’s capacity to learn new things and adjust to new situations decreases, so you could also be unhappy living in a hugely different world to the one you grew up in.
How long is it likely to be before bioprinted organs and body parts are widely available?
Although many biotechnology companies are working on it and the financial rewards would be large, it will probably be decades before that is a possibility. Printing with living cells is much more complex than printing objects in plastic.

Word Watch

Bioprinting
Creating living tissue with a 3D printer, layer by layer, for research, drug development and testing, and ultimately for producing replacement organs for transplants. They could be made on demand from patients’ own cells and thus would not be rejected by their immune systems.
Congenital
A congenital disease is one which is present when a baby is born or which appears shortly after.
Transplant
The first successful organ transplant was carried out in 1954. As it was between genetically identical twins, the donor kidney was not rejected by the patient’s immune system. The first successful heart transplant took place in 1967. The patient survived 18 days. Improvements in suppressing the body’s rejection of the organ mean that today tens of thousands of transplants are performed each year worldwide with good survival rates.

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